Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis

OBJECTIVE: We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, and memory impairment in a rat sepsis model of cecal ligation and puncture (CLP)-induced polymicrobial peritonitis. METHODS: Twenty-four rats were assigned to sham, CLP, CLP +...

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Detalles Bibliográficos
Publicado en:J Int Med Res
Main Authors: Bedirli, Nurdan, Bagriacik, Emin Umit, Yilmaz, Guldal, Ozkose, Zerrin, Kavutçu, Mustafa, Cavunt Bayraktar, Aslı, Bedirli, Abdulkadir
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2018
Assuntos:
Pre-Clinical Research Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6124281/
https://ncbi.nlm.nih.gov/pubmed/29756489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060518773265
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