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The spliceosome as a new therapeutic vulnerability in aggressive prostate cancer

Alternative splicing (AS) analysis across the entire spectrum of human prostate cancer evolution reveals the unexpected findings that intron retention is a hallmark of stemness and tumor aggressiveness, and androgen receptor controls a splicing program distinct from its transcriptional regulation. I...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Zou, Cheng, Zhang, Dingxiao
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469601/
https://ncbi.nlm.nih.gov/pubmed/32944637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1778420
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