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RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells

Ferroptosis is a recently discovered form of programmed cell death, but its regulatory mechanisms remain poorly understood. Here, we show that the RNA-binding protein ZFP36/TTP (ZFP36 ring finger protein) plays a crucial role in regulating ferroptosis in hepatic stellate cells (HSCs). Upon exposure...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Zili, Guo, Mei, Li, Yujia, Shen, Min, Kong, Desong, Shao, Jiangjuan, Ding, Hai, Tan, Shanzhong, Chen, Anping, Zhang, Feng, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469536/
https://ncbi.nlm.nih.gov/pubmed/31679460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1687985
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