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Dynamic modulation of autophagy: implications for aging and cancer

Reduced autophagy has been implicated in aging, yet whether its loss can promote aging phenotypes and pathologies in mammals, and how reversible this process is, has never been fully explored. Using inducible short hairpin RNA (shRNA) mouse models, we have recently shown that autophagy inhibition ac...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Cassidy, Liam D., Narita, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469470/
https://ncbi.nlm.nih.gov/pubmed/32944616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1754723
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