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Dynamic modulation of autophagy: implications for aging and cancer

Reduced autophagy has been implicated in aging, yet whether its loss can promote aging phenotypes and pathologies in mammals, and how reversible this process is, has never been fully explored. Using inducible short hairpin RNA (shRNA) mouse models, we have recently shown that autophagy inhibition ac...

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Библиографические подробности
Опубликовано в: :Mol Cell Oncol
Главные авторы: Cassidy, Liam D., Narita, Masashi
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469470/
https://ncbi.nlm.nih.gov/pubmed/32944616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1754723
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