Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease

BACKGROUND: Identifying and understanding the functional role of genetic risk factors for Alzheimer disease (AD) has been complicated by the variability of genetic influences across brain regions and confounding with age-related neurodegeneration. METHODS: A gene co-expression network was constructe...

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Publicado en:Alzheimers Res Ther
Main Authors: Lancour, Daniel, Dupuis, Josée, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Schellenberg, Gerard C., Crovella, Mark, Farrer, Lindsay A., Kasif, Simon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469336/
https://ncbi.nlm.nih.gov/pubmed/32878640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00674-7
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