Visible Photorelease of Liquid Biopsy Markers following Microfluidic Affinity-Enrichment

We detail a heterobifunctional, 7-aminocoumarin photocleavable (PC) linker with unique properties to covalently attach Abs to surfaces and subsequently release them with visible light (400–450 nm). The PC linker allowed rapid (2 min) and efficient (>90%) release of CTCs and EVs without damaging t...

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Bibliografische gegevens
Gepubliceerd in:Chem Commun (Camb)
Hoofdauteurs: Pahattuge, Thilanga N., Jackson, J. Matt, Rane, Digamber, Wijerathne, Harshani, Brown, Virginia, Witek, Malgorzata A., Perera, Chamani, Givens, Richard S., Peterson, Blake R., Soper, Steven A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469076/
https://ncbi.nlm.nih.gov/pubmed/32163053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc09598e
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