Visible Photorelease of Liquid Biopsy Markers following Microfluidic Affinity-Enrichment

We detail a heterobifunctional, 7-aminocoumarin photocleavable (PC) linker with unique properties to covalently attach Abs to surfaces and subsequently release them with visible light (400–450 nm). The PC linker allowed rapid (2 min) and efficient (>90%) release of CTCs and EVs without damaging t...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Pahattuge, Thilanga N., Jackson, J. Matt, Rane, Digamber, Wijerathne, Harshani, Brown, Virginia, Witek, Malgorzata A., Perera, Chamani, Givens, Richard S., Peterson, Blake R., Soper, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469076/
https://ncbi.nlm.nih.gov/pubmed/32163053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc09598e
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