Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney disease

Inflammation is a major determinant for the progression of chronic kidney disease (CKD). NF-κB is a master transcription factor upregulated in CKD that promotes inflammation and regulates apoptosis and vascular remodeling. We aimed to modulate this pathway for CKD therapy in a swine model of CKD usi...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Chade, Alejandro R., Williams, Maxx L., Engel, Jason E., Williams, Erika, Bidwell, Gene L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468833/
https://ncbi.nlm.nih.gov/pubmed/32538151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00155.2020
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