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Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney disease
Inflammation is a major determinant for the progression of chronic kidney disease (CKD). NF-κB is a master transcription factor upregulated in CKD that promotes inflammation and regulates apoptosis and vascular remodeling. We aimed to modulate this pathway for CKD therapy in a swine model of CKD usi...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7468833/ https://ncbi.nlm.nih.gov/pubmed/32538151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00155.2020 |
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