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Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils

Amyloidogenic protein assembly into insoluble fibrillar aggregates is linked with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease, affecting millions of people worldwide. The search for a potential anti-amyloid drug has led to the discovery of hundreds of compounds, n...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sakalauskas, Andrius, Ziaunys, Mantas, Smirnovas, Vytautas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468289/
https://ncbi.nlm.nih.gov/pubmed/32879381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70982-3
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