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Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils

Amyloidogenic protein assembly into insoluble fibrillar aggregates is linked with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease, affecting millions of people worldwide. The search for a potential anti-amyloid drug has led to the discovery of hundreds of compounds, n...

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Publicat a:Sci Rep
Autors principals: Sakalauskas, Andrius, Ziaunys, Mantas, Smirnovas, Vytautas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468289/
https://ncbi.nlm.nih.gov/pubmed/32879381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70982-3
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