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Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils

Amyloidogenic protein assembly into insoluble fibrillar aggregates is linked with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease, affecting millions of people worldwide. The search for a potential anti-amyloid drug has led to the discovery of hundreds of compounds, n...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakalauskas, Andrius, Ziaunys, Mantas, Smirnovas, Vytautas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468289/
https://ncbi.nlm.nih.gov/pubmed/32879381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70982-3
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