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Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils

Amyloidogenic protein assembly into insoluble fibrillar aggregates is linked with several neurodegenerative disorders, such as Alzheimer’s or Parkinson’s disease, affecting millions of people worldwide. The search for a potential anti-amyloid drug has led to the discovery of hundreds of compounds, n...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Sakalauskas, Andrius, Ziaunys, Mantas, Smirnovas, Vytautas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468289/
https://ncbi.nlm.nih.gov/pubmed/32879381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70982-3
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