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Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin

Etimicin (ETM), a fourth-generation aminoglycosides (AGs), is now widely clinically used in China due to its high efficacy and low toxicity. However, the mechanisms underlying its low nephrotoxicity and ototoxicity remain unclear. In the present study we compared the antibacterial and toxicity profi...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yao, Lan, Zhang, Jing-wei, Chen, Bin, Cai, Ming-min, Feng, Dong, Wang, Qi-zhi, Wang, Xin-yu, Sun, Jian-guo, Zheng, Yi-wen, Wang, Guang-ji, Zhou, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468263/
https://ncbi.nlm.nih.gov/pubmed/31937930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0342-5
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