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Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways

The antidiabetic drug canagliflozin is reported to possess several cardioprotective effects. However, no studies have investigated protective effects of canagliflozin in isoprenaline (ISO)-induced cardiac oxidative damage—a model mimicking sympathetic nervous system (SNS) overstimulation-evoked card...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hasan, Raquibul, Lasker, Shoumen, Hasan, Ahasanul, Zerin, Farzana, Zamila, Mushfera, Chowdhury, Faizul Islam, Nayan, Shariful Islam, Rahman, Md. Mizanur, Khan, Ferdous, Subhan, Nusrat, Alam, Md. Ashraful
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468124/
https://ncbi.nlm.nih.gov/pubmed/32879422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71449-1
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