Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration

The primary cilium (PC) is a small centrosome-assembled organelle, protruding from the surface of most eukaryotic cells. It plays a key role in cell migration, but the underlying mechanisms are unknown. Here, we show that the PC regulates neuronal migration via cyclic adenosine 3’-5’ monosphosphate...

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Vydáno v:Sci Adv
Hlavní autoři: Stoufflet, Julie, Chaulet, Maxime, Doulazmi, Mohamed, Fouquet, Coralie, Dubacq, Caroline, Métin, Christine, Schneider-Maunoury, Sylvie, Trembleau, Alain, Vincent, Pierre, Caillé, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467704/
https://ncbi.nlm.nih.gov/pubmed/32917588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba3992
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