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The Promise for Histone Methyltransferase Inhibitors for Epigenetic Therapy in Clinical Oncology: A Narrative Review

Epigenetic processes are essential for normal development and the maintenance of tissue-specific gene expression in mammals. Changes in gene expression and malignant cellular transformation can result from disruption of epigenetic mechanisms, and global disruption in the epigenetic landscape is a ke...

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Vydáno v:Adv Ther
Hlavní autoři: Rugo, Hope S., Jacobs, Ira, Sharma, Shikhar, Scappaticci, Frank, Paul, Thomas A., Jensen-Pergakes, Kristen, Malouf, Gabriel G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Healthcare 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467409/
https://ncbi.nlm.nih.gov/pubmed/32445185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-020-01379-x
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