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Cryo-EM as a powerful tool for drug discovery
The recent revolution in cryo-EM has produced an explosion of structures at near-atomic or better resolution. This has allowed cryo-EM structures to provide visualization of bound small-molecule ligands in the macromolecules, and these new structures have provided unprecedented insights into the mol...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Ltd.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467112/ https://ncbi.nlm.nih.gov/pubmed/32890683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127524 |
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