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Propagation of Conformational Coordinates Across Angular Space in Mapping the Continuum of States from Cryo-EM Data by Manifold Embedding

Recent approaches to the study of biological molecules employ manifold learning to single-particle cryo-EM datasets to map the continuum of states of a molecule into a low-dimensional space spanned by eigenvectors, or “conformational coordinates”. This is done separately for each projection directio...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Maji, Suvrajit, Liao, Hstau, Dashti, Ali, Mashayekhi, Ghoncheh, Ourmazd, Abbas, Frank, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466846/
https://ncbi.nlm.nih.gov/pubmed/32207941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b01115
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