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Energy Landscape of the SARS-CoV-2 Reveals Extensive Conformational Heterogeneity

Cryo-electron microscopy (cryo-EM) has produced a number of structural models of the SARS-CoV-2 spike, already prompting biomedical outcomes. However, these reported models and their associated electrostatic potential maps represent an unknown admixture of conformations stemming from the underlying...

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Bibliografski detalji
Izdano u:bioRxiv
Glavni autori: Mashayekhi, Ghoncheh, Vant, John, Singharoy, Abhishek, Ourmazd, Abbas
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132221/
https://ncbi.nlm.nih.gov/pubmed/34013265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.11.443708
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