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Role of the PD-1/PD-L1 Dyad in the Maintenance of Pancreatic Immune Tolerance for Prevention of Type 1 Diabetes

The human pancreas, like almost all organs in the human body, is immunologically tolerated despite the presence of innate and adaptive immune cells that promptly mediate protective immune responses against pathogens in situ. The PD-1/PD-L1 inhibitory pathway seems to play a key role in the maintenan...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Falcone, Marika, Fousteri, Georgia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466754/
https://ncbi.nlm.nih.gov/pubmed/32973682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00569
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