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Role of the PD-1/PD-L1 Dyad in the Maintenance of Pancreatic Immune Tolerance for Prevention of Type 1 Diabetes

The human pancreas, like almost all organs in the human body, is immunologically tolerated despite the presence of innate and adaptive immune cells that promptly mediate protective immune responses against pathogens in situ. The PD-1/PD-L1 inhibitory pathway seems to play a key role in the maintenan...

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Détails bibliographiques
Publié dans:Front Endocrinol (Lausanne)
Auteurs principaux: Falcone, Marika, Fousteri, Georgia
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466754/
https://ncbi.nlm.nih.gov/pubmed/32973682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00569
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