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Toward a Systematic Structural and Functional Annotation of Solute Carriers Transporters—Example of the SLC6 and SLC7 Families

SLC transporters are emerging key drug targets. One important step for drug development is the profound understanding of the structural determinants defining the substrate selectivity of each transporter. Recently, the improvement of computational power and experimental methods such as X-ray and cry...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Autor principal: Colas, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466448/
https://ncbi.nlm.nih.gov/pubmed/32973497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01229
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