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Mathematical Modeling of MPNs Offers Understanding and Decision Support for Personalized Treatment

(1) Background: myeloproliferative neoplasms (MPNs) are slowly developing hematological cancers characterized by few driver mutations, with JAK2V617F being the most prevalent. (2) Methods: using mechanism-based mathematical modeling (MM) of hematopoietic stem cells, mutated hematopoietic stem cells,...

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Publicat a:Cancers (Basel)
Autors principals: Ottesen, Johnny T., Pedersen, Rasmus K., Dam, Marc J. B., Knudsen, Trine A., Skov, Vibe, Kjær, Lasse, Andersen, Morten
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466162/
https://ncbi.nlm.nih.gov/pubmed/32751766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082119
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