Data‐driven analysis of JAK2V617F kinetics during interferon‐alpha2 treatment of patients with polycythemia vera and related neoplasms

Treatment with PEGylated interferon‐alpha2 (IFN) of patients with essential thrombocythemia and polycythemia vera induces major molecular remissions with a reduction in the JAK2V617F allele burden to undetectable levels in a subset of patients. A favorable response to IFN has been argued to depend u...

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Publicat a:Cancer Med
Autors principals: Pedersen, Rasmus K., Andersen, Morten, Knudsen, Trine A., Sajid, Zamra, Gudmand‐Hoeyer, Johanne, Dam, Marc J. B., Skov, Vibe, Kjær, Lasse, Ellervik, Christina, Larsen, Thomas S., Hansen, Dennis, Pallisgaard, Niels, Hasselbalch, Hans C., Ottesen, Johnny T.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Clinical Cancer Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064092/
https://ncbi.nlm.nih.gov/pubmed/31991066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2741
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