Data‐driven analysis of JAK2V617F kinetics during interferon‐alpha2 treatment of patients with polycythemia vera and related neoplasms

Treatment with PEGylated interferon‐alpha2 (IFN) of patients with essential thrombocythemia and polycythemia vera induces major molecular remissions with a reduction in the JAK2V617F allele burden to undetectable levels in a subset of patients. A favorable response to IFN has been argued to depend u...

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Udgivet i:Cancer Med
Main Authors: Pedersen, Rasmus K., Andersen, Morten, Knudsen, Trine A., Sajid, Zamra, Gudmand‐Hoeyer, Johanne, Dam, Marc J. B., Skov, Vibe, Kjær, Lasse, Ellervik, Christina, Larsen, Thomas S., Hansen, Dennis, Pallisgaard, Niels, Hasselbalch, Hans C., Ottesen, Johnny T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Clinical Cancer Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064092/
https://ncbi.nlm.nih.gov/pubmed/31991066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2741
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