Engineering a Humanised Niche to Support Human Haematopoiesis in Mice: Novel Opportunities in Modelling Cancer

Despite the bone marrow microenvironment being widely recognised as a key player in cancer research, the current animal models that represent a human haematopoietic system lack the contribution of the humanised marrow microenvironment. Here we describe a murine model that relies on the combination o...

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Publicado en:Cancers (Basel)
Autores principales: Sanchez-Herrero, Alvaro, Calvo, Isabel A., Flandes-Iparraguirre, Maria, Landgraf, Marietta, Lahr, Christoph A., Shafiee, Abbas, Granero-Molto, Froilán, Saez, Borja, Mazo, Manuel M., Paiva, Bruno, de Juan Pardo, Elena, Nicol, Andrew, Prosper, Felipe, Bray, Laura J., McGovern, Jacqui A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466161/
https://ncbi.nlm.nih.gov/pubmed/32781703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082205
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