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A perisinusoidal niche for extramedullary haematopoiesis in the spleen

Haematopoietic stresses mobilize haematopoietic stem cells (HSCs) from the bone marrow to the spleen and induce extramedullary haematopoiesis (EMH). However, the cellular nature of the EMH niche is unknown. Here, we assessed the sources of the key niche factors, SCF and CXCL12, in the mouse spleen a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Inra, Christopher N., Zhou, Bo O., Acar, Melih, Murphy, Malea M., Richardson, James, Zhao, Zhiyu, Morrison, Sean J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838203/
https://ncbi.nlm.nih.gov/pubmed/26570997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15530
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