Infection and Activation of B Cells by Theiler’s Murine Encephalomyelitis Virus (TMEV) Leads to Autoantibody Production in an Infectious Model of Multiple Sclerosis

Theiler’s murine encephalomyelitis virus (TMEV) induces immune-mediated inflammatory demyelinating disease in susceptible mice that is similar to human multiple sclerosis (MS). In light of anti-CD20 therapies for MS, the susceptibility of B cells to TMEV infection is particularly important. In our s...

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Publicado en:Cells
Autores principales: Jin, Young-Hee, Kim, Charles X., Huang, Jocelin, Kim, Byung S.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465974/
https://ncbi.nlm.nih.gov/pubmed/32727036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081787
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