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The role of α4 integrin in Theiler’s murine encephalomyelitis virus (TMEV)-induced demyelinating disease: an infectious animal model for multiple sclerosis (MS)

Natalizumab, which is an antibody against α4 integrin, has been used for the treatment of multiple sclerosis (MS). In the present study, we investigated both the role of α4 integrin and the therapeutic effect of HCA3551, a newly synthesized orally active small-molecule α4 integrin antagonist, in the...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Hirano, Yuta, Kobayashi, Kunitoshi, Tomiki, Hiroki, Inaba, Yuhji, Ichikawa, Motoki, Kim, Byung S., Koh, Chang-Sung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108629/
https://ncbi.nlm.nih.gov/pubmed/27803063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw045
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