Predicting the Role of DNA Polymerase β Alone or with KRAS Mutations in Advanced NSCLC Patients Receiving Platinum-Based Chemotherapy

Clinical data suggest that only a subgroup of non-small cell lung cancer (NSCLC) patients has long-term benefits after front-line platinum-based therapy. We prospectively investigate whether KRAS status and DNA polymerase β expression could help identify patients responding to platinum compounds. Pr...

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Pubblicato in:J Clin Med
Autori principali: Alvisi, Maria Francesca, Ganzinelli, Monica, Linardou, Helena, Caiola, Elisa, Lo Russo, Giuseppe, Cecere, Fabiana Letizia, Bettini, Anna Cecilia, Psyrri, Amanda, Milella, Michele, Rulli, Eliana, Fabbri, Alessandra, De Maglie, Marcella, Romanelli, Pierpaolo, Murray, Samuel, Ndembe, Gloriana, Broggini, Massimo, Garassino, Marina Chiara, Marabese, Mirko
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465625/
https://ncbi.nlm.nih.gov/pubmed/32751518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9082438
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