Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling

We previously reported that serine-47 (S47) phosphorylation of cytochrome c (Cytc) in the brain results in lower cytochrome c oxidase (COX) activity and caspase-3 activity in vitro. We here analyze the effect of S47 modification in fibroblast cell lines stably expressing S47E phosphomimetic Cytc, un...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cells
Autores principales: Kalpage, Hasini A., Wan, Junmei, Morse, Paul T., Lee, Icksoo, Hüttemann, Maik
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465522/
https://ncbi.nlm.nih.gov/pubmed/32781572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081843
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares