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Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity

Cytochrome c (Cytc) is a multifunctional protein that operates as an electron carrier in the mitochondrial electron transport chain and plays a key role in apoptosis. We have previously shown that tissue-specific phosphorylations of Cytc in the heart, liver, and kidney play an important role in the...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Kalpage, Hasini A., Vaishnav, Asmita, Liu, Jenney, Varughese, Ashwathy, Wan, Junmei, Turner, Alice A., Ji, Qinqin, Zurek, Matthew P., Kapralov, Alexandr A., Kagan, Valerian E., Brunzelle, Joseph S., Recanati, Maurice-Andre, Grossman, Lawrence I., Sanderson, Thomas H., Lee, Icksoo, Salomon, Arthur R., Edwards, Brian F. P., Hüttemann, Maik
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894086/
https://ncbi.nlm.nih.gov/pubmed/31570002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901120R
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