Preparation and Evaluation of Eudragit L100-PEG Proliponiosomes for Enhanced Oral Delivery of Celecoxib

PEGylated Eudragit L100 (ELP)-containing proliponiosomes (PLNs) were developed for improved oral delivery of celecoxib (CXB). The successful introduction of PEG 2000 or 5000 to Eudragit L100 (EL) was confirmed via proton nuclear magnetic resonance analysis of which calculated molar substitution rati...

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Publié dans:Pharmaceutics
Auteurs principaux: Kim, Min-Hwan, Kim, Dong Hyun, Nguyen, Duy-Thuc, Lee, Han Sol, Kang, Nae-Won, Baek, Min-Jun, An, Jiseon, Yoo, So-Yeol, Mun, Yong-Hyeon, Lee, Wonhwa, Kim, Ki-Taek, Cho, Cheong-Weon, Lee, Jae-Young, Kim, Dae-Duk
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465340/
https://ncbi.nlm.nih.gov/pubmed/32751591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080718
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