Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

Some colorectal cancer patients harboring FGFR (fibroblast growth factor receptor) genetic alterations, such as copy number gain, mutation, and/or mRNA overexpression, were selected for enrollment in several recent clinical trials of FGFR inhibitor, because these genetic alterations were preclinical...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Yamamoto, Takehito, Miyoshi, Hiroyuki, Kakizaki, Fumihiko, Maekawa, Hisatsugu, Yamaura, Tadayoshi, Morimoto, Tomonori, Katayama, Toshiro, Kawada, Kenji, Sakai, Yoshiharu, Taketo, M. Mark
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465102/
https://ncbi.nlm.nih.gov/pubmed/32708005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082010
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