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Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

Some colorectal cancer patients harboring FGFR (fibroblast growth factor receptor) genetic alterations, such as copy number gain, mutation, and/or mRNA overexpression, were selected for enrollment in several recent clinical trials of FGFR inhibitor, because these genetic alterations were preclinical...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yamamoto, Takehito, Miyoshi, Hiroyuki, Kakizaki, Fumihiko, Maekawa, Hisatsugu, Yamaura, Tadayoshi, Morimoto, Tomonori, Katayama, Toshiro, Kawada, Kenji, Sakai, Yoshiharu, Taketo, M. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465102/
https://ncbi.nlm.nih.gov/pubmed/32708005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082010
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