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The Multifaceted Histidine-Based Carriers for Nucleic Acid Delivery: Advances and Challenges

Histidines incorporated into carriers of nucleic acids may enhance the extracellular stability of the nanoparticle, yet aid in the intracellular disruption of the nanoparticle, enabling the release of the nucleic acid. Moreover, protonation of histidines in the endosomes may result in endosomal swel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceutics
Main Authors: He, Jiaxi, Xu, Songhui, Mixson, A. James
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465012/
https://ncbi.nlm.nih.gov/pubmed/32823960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080774
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