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The Multifaceted Histidine-Based Carriers for Nucleic Acid Delivery: Advances and Challenges

Histidines incorporated into carriers of nucleic acids may enhance the extracellular stability of the nanoparticle, yet aid in the intracellular disruption of the nanoparticle, enabling the release of the nucleic acid. Moreover, protonation of histidines in the endosomes may result in endosomal swel...

詳細記述

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書誌詳細
出版年:Pharmaceutics
主要な著者: He, Jiaxi, Xu, Songhui, Mixson, A. James
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465012/
https://ncbi.nlm.nih.gov/pubmed/32823960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080774
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