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The Multifaceted Histidine-Based Carriers for Nucleic Acid Delivery: Advances and Challenges
Histidines incorporated into carriers of nucleic acids may enhance the extracellular stability of the nanoparticle, yet aid in the intracellular disruption of the nanoparticle, enabling the release of the nucleic acid. Moreover, protonation of histidines in the endosomes may result in endosomal swel...
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| 出版年: | Pharmaceutics |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7465012/ https://ncbi.nlm.nih.gov/pubmed/32823960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12080774 |
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