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Peptidoglycan editing by a specific LD-transpeptidase controls the muramidase-dependent secretion of typhoid toxin

Protein secretion mechanisms are essential for the virulence of most bacterial pathogens. Typhoid toxin is an essential virulence factor for Salmonella Typhi, the cause of typhoid fever in humans. This toxin is unique in that it is only produced within mammalian cells, and it must be trafficked to t...

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Detalles Bibliográficos
Publicado en:Nat Microbiol
Main Authors: Geiger, Tobias, Pazos, Manuel, Lara-Tejero, Maria, Vollmer, Waldemar, Galán, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464686/
https://ncbi.nlm.nih.gov/pubmed/30250245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0248-x
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