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Peptidoglycan editing by a specific LD-transpeptidase controls the muramidase-dependent secretion of typhoid toxin

Protein secretion mechanisms are essential for the virulence of most bacterial pathogens. Typhoid toxin is an essential virulence factor for Salmonella Typhi, the cause of typhoid fever in humans. This toxin is unique in that it is only produced within mammalian cells, and it must be trafficked to t...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Geiger, Tobias, Pazos, Manuel, Lara-Tejero, Maria, Vollmer, Waldemar, Galán, Jorge E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464686/
https://ncbi.nlm.nih.gov/pubmed/30250245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0248-x
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