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A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, the former established as a transcription regulator. Genome wide CpG methylation, summarized over GBs and CGIs, was analyzed for impact on overall survival (OS) in...

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Pils, Dietmar, Steindl, Elisabeth, Bachmayr-Heyda, Anna, Dekan, Sabine, Aust, Stefanie
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464642/
https://ncbi.nlm.nih.gov/pubmed/32806596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082257
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