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A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, the former established as a transcription regulator. Genome wide CpG methylation, summarized over GBs and CGIs, was analyzed for impact on overall survival (OS) in...

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Publicat a:Cancers (Basel)
Autors principals: Pils, Dietmar, Steindl, Elisabeth, Bachmayr-Heyda, Anna, Dekan, Sabine, Aust, Stefanie
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464642/
https://ncbi.nlm.nih.gov/pubmed/32806596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082257
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