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A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, the former established as a transcription regulator. Genome wide CpG methylation, summarized over GBs and CGIs, was analyzed for impact on overall survival (OS) in...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pils, Dietmar, Steindl, Elisabeth, Bachmayr-Heyda, Anna, Dekan, Sabine, Aust, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464642/
https://ncbi.nlm.nih.gov/pubmed/32806596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082257
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