Metformin and Everolimus: A Promising Combination for Neuroendocrine Tumors Treatment

Introduction: Treatment options for neuroendocrine tumors (NETs) are rarely curative, as NETs frequently show resistance to medical therapy. The use of everolimus, an mTOR inhibitor, is limited by the development of resistance, probably due to the activation of Akt signaling. In this context, the an...

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Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Vitali, Eleonora, Boemi, Ilena, Tarantola, Giulia, Piccini, Sara, Zerbi, Alessandro, Veronesi, Giulia, Baldelli, Roberto, Mazziotti, Gherardo, Smiroldo, Valeria, Lavezzi, Elisabetta, Spada, Anna, Mantovani, Giovanna, Lania, Andrea G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464161/
https://ncbi.nlm.nih.gov/pubmed/32748870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082143
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