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Everolimus in the management of metastatic neuroendocrine tumours

Neuroendocrine tumours are increasing in incidence and cause a variety of symptoms. The mammalian target of rapamycin (mTOR) pathway plays a key role in neuroendocrine tumour (NET) pathogenesis, leading to increased lipid synthesis, protein synthesis and cellular growth. Upregulation of this pathway...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: David L. Chan, Eva Segelov, Simron Singh
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2017-01-01
Schriftenreihe:Therapeutic Advances in Gastroenterology
Online Zugang:https://doi.org/10.1177/1756283X16674660
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