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Everolimus in the management of metastatic neuroendocrine tumours

Neuroendocrine tumours are increasing in incidence and cause a variety of symptoms. The mammalian target of rapamycin (mTOR) pathway plays a key role in neuroendocrine tumour (NET) pathogenesis, leading to increased lipid synthesis, protein synthesis and cellular growth. Upregulation of this pathway...

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Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Chan, David L., Segelov, Eva, Singh, Simron
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330615/
https://ncbi.nlm.nih.gov/pubmed/28286565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16674660
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