Phenotypic and Functional Characterization of NK Cells in αβT-Cell and B-Cell Depleted Haplo-HSCT to Cure Pediatric Patients with Acute Leukemia

NK cells can exert remarkable graft-versus-leukemia (GvL) effect in HLA-haploidentical hematopoietic stem cell transplantation (haplo-HSCT). Here, we dissected the NK-cell repertoire of 80 pediatric acute leukemia patients previously reported to have an excellent clinical outcome after αβT/B-deplete...

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Publicado en:Cancers (Basel)
Main Authors: Meazza, Raffaella, Falco, Michela, Loiacono, Fabrizio, Canevali, Paolo, Della Chiesa, Mariella, Bertaina, Alice, Pagliara, Daria, Merli, Pietro, Indio, Valentina, Galaverna, Federica, Algeri, Mattia, Moretta, Francesca, Colomar-Carando, Natalia, Muccio, Letizia, Sivori, Simona, Pession, Andrea, Mingari, Maria Cristina, Moretta, Lorenzo, Moretta, Alessandro, Locatelli, Franco, Pende, Daniela
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463940/
https://ncbi.nlm.nih.gov/pubmed/32764469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082187
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