Zoledronic acid boosts γδ T-cell activity in children receiving αβ(+) T and CD19(+) cell-depleted grafts from an HLA-haplo-identical donor

We demonstrated that γδ T cells of patients given HLA-haploidentical HSCT after removal of αβ(+) T cells and CD19(+) B cells are endowed with the capacity of killing leukemia cells after ex vivo treatment with zoledronic acid (ZOL). Thus, we tested the hypothesis that infusion of ZOL in patients rec...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Bertaina, A., Zorzoli, A., Petretto, A., Barbarito, G., Inglese, E., Merli, P., Lavarello, C., Brescia, L. P., De Angelis, B., Tripodi, G., Moretta, L., Locatelli, F., Airoldi, I.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353934/
https://ncbi.nlm.nih.gov/pubmed/28344861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1216291
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