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Anti-Proliferative Effect of Statins Is Mediated by DNMT1 Inhibition and p21 Expression in OSCC Cells

Statins, also known as HMG-CoA reductase inhibitors, are a class of cholesterol-lowering drugs and their anti-cancer effects have been studied in different types of malignant diseases. In the present study, we investigated the anti-proliferative effects of statins, including cerivastatin and simvast...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Dongoran, Rachmad Anres, Wang, Kai-Hung, Lin, Tsung-Jen, Yuan, Ta-Chun, Liu, Chin-Hung
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463937/
https://ncbi.nlm.nih.gov/pubmed/32731382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082084
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