TLR Antagonism by Sparstolonin B Alters Microbial Signature and Modulates Gastrointestinal and Neuronal Inflammation in Gulf War Illness Preclinical Model

The 1991 Persian Gulf War veterans presented a myriad of symptoms that ranged from chronic pain, fatigue, gastrointestinal disturbances, and cognitive deficits. Currently, no therapeutic regimen exists to treat the plethora of chronic symptoms though newer pharmacological targets such as microbiome...

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Veröffentlicht in:Brain Sci
Hauptverfasser: Bose, Dipro, Mondal, Ayan, Saha, Punnag, Kimono, Diana, Sarkar, Sutapa, Seth, Ratanesh K., Janulewicz, Patricia, Sullivan, Kimberly, Horner, Ronnie, Klimas, Nancy, Nagarkatti, Mitzi, Nagarkatti, Prakash, Chatterjee, Saurabh
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463890/
https://ncbi.nlm.nih.gov/pubmed/32784362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci10080532
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