Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis

BACKGROUND: Recent clinical and basic research implicated a strong correlation between NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and neurodegeneration, but the mediators and critical pathways involved are not well understood. Lipocalin 2 (Lcn2) is one of the impor...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Mondal, Ayan, Bose, Dipro, Saha, Punnag, Sarkar, Sutapa, Seth, Ratanesh, Kimono, Diana, Albadrani, Muayad, Nagarkatti, Mitzi, Nagarkatti, Prakash, Chatterjee, Saurabh
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335438/
https://ncbi.nlm.nih.gov/pubmed/32622362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01876-4
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