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Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles
An efficient construction of imidazole ring by a Cs(2)CO(3)-promoted annulation of amidoximes with terminal alkynes in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted imidazoles in good yields under transition...
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| Izdano u: | Molecules |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7463794/ https://ncbi.nlm.nih.gov/pubmed/32784900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163621 |
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