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Quinazolinone Synthesis through Base-Promoted S(N)Ar Reaction of ortho-Fluorobenzamides with Amides Followed by Cyclization

[Image: see text] A transition-metal-free synthesis of quinazolin-4-ones by Cs(2)CO(3)-promoted S(N)Ar reaction of ortho-fluorobenzamides with amides followed by cyclization in dimethyl sulfoxide has been developed. The present procedure can provide efficient synthetic methods for the formation of b...

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Bibliografiset tiedot
Julkaisussa:ACS Omega
Päätekijät: Iqbal, Muhammad Asif, Lu, Le, Mehmood, Hina, Khan, Dost Muhammad, Hua, Ruimao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647956/
https://ncbi.nlm.nih.gov/pubmed/31459909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00699
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